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AccuStandard | Per- and Polyfluoroalkyl Substance Standards (PFAS)
Per- and polyfluoroalkyl substances (PFAS) belong to a continuously expanding family of thousands of man-made chemical pollutants. The amphiphilic ability of PFAS has led to the manufacturing of PFAS in oils and water-resistant industrial and consumer products such as firefighting foams, cleaners, cosmetics, paints, adhesives, non-stick coatings and insecticides. However, environmental chemists and biologists have uncovered that PFAS have harmful toxicological effects and pose a significant risk to the public. The high thermal and chemical stability of PFAS make them persistent in the environment and nearly non-biodegradable, necessitating chemical reference standards to monitor for PFAS in drinking water, burn sites and teflon products.
Find Per- and Polyfluoroalkyl Substanstances (PFAS) Standards by Type
EPA Methods
ASTM Methods
ISO Methods
FDA Methods
AOAC Methods
Massachusetts PFAS Standard
PFAS Single Component Standards
EPA Methods
To reduce exposure to PFAS, USEPA has published Method 533 to test for 25 PFAS in Drinking Water. Our M-533 PFAS CRM is formulated to include all target analytes required by this method.
EPA Method 533
Method 533 Standard | M-533
2 μg/mL each in MeOH, 25 comps. | Purchase
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid
9-Chlorohexadecafluoro-3-oxanone-1-sulfonic acid
4,8-Dioxa-3H-perfluorononanoic acid
Perfluoro(2-methyl-3-oxahexanoic) acid
Nonafluoro-3,6-dioxaheptanoic acid
Perfluoro-n-butanoic acid
Perfluorobutane-1-sulfonic acid
1H,1H,2H,2H-Perfluorodecanesulfonic acid
Perfluoro-n-decanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro(2-ethoxyethane)sulphonic acid
Perfluoroheptanesulfonic acid
Perfluoro-n-heptanoic acid
1H,1H,2H,2H-Perfluorohexanesulfonic acid
Perfluorohexane-1-sulfonic acid
Perfluoro-n-hexanoic acid
Perfluoro-3-methoxypropanoic acid
Perfluoro(4-methoxybutanoic) acid
Perfluoro-n-nonanoic acid
1H,1H,2H,2H-Perfluorooctane sulfonic acid
Perfluorooctane-1-sulfonic acid
Perfluoro-n-octanoic acid
Perfluoro-n-pentanoic acid
Perfluoropentanesulfonic acid
Perfluoro-n-undecanoic acid
This updated version of method 537 can be used for the quantitative analysis of 18 analytes by Solid Phase Extraction (SPE) and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS).
EPA Method 537.1 Standard (UPDATED)
Method 537.1 Standard | M-537.1
2 μg/mL each in MeOH, 18 comps. | Purchase
Perfluoro(2-methyl-3-oxahexanoic) acid
N-ethylperfluoro-1-octanesulfonamidoacetic acid
N-methylperfluoro-1-octanesulfonamidoacetic acid
Perfluorobutane-1-sulfonic acid
Perfluoro-n-decanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-heptanoic acid
Perfluorohexane-1-sulfonic acid
Perfluoro-n-hexanoic acid
Perfluoro-n-nonanoic acid
Perfluorooctane-1-sulfonic acid
Perfluoro-n-octanoic acid
Perfluoro-n-tetradecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-undecanoic acid
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid
9-Chlorohexadecafluoro-3-oxanone-1-sulfonic acid
4,8-Dioxa-3H-perfluorononanoic acid
This was the first method introduced for the determination of 14 PFAS in drinking water. It includes 14 PFAS for determination using Solid Phase Extraction (SPE) and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS). This method was updated in 2018 to 537.1 which adds additional analytes.
Method 537 Native Compound Standard | M-537
50 μg/mL each in AcCN:Water (95:5), 14 comps. | Purchase
Perfluoro-n-hexanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-decanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-tetradecanoic acid
N-Methylperfluorooctanesulfonamidoacetic acid
N-Ethylperfluorooctanesulfonamidoacetic acid
Perfluoro-n-butane sulfonic acid
Perfluoro-n-hexane sulfonic acid
Perfluoro-n-octane sulfonic acid
This Certified Reference Material (CRM) contains the 24 PFAS based on the newest publication of USEPA Method 8327 which is suitable for testing PFAS in surface water, groundwater and wastewater matrices. Our two CRMs M-8327-10X and M-8327 are offered at a high and a low concentration to meet the specific needs of your testing. Both CRMs are stabilized with NaOH to enhance product stability.
Method 8327 Native PFAS Standard | M-8327
2 μg/mL in Methanol, 24 comps.| Purchase
Perfluorobutane-1-sulfonic acid
Perfluoropentanesulfonic acid
Perfluorohexane-1-sulfonic acid
Perfluoroheptanesulfonic acid
Perfluorooctane-1-sulfonic acid
Perfluorononanesulfonic acid
Perfluorodecane-1-sulfonic acid
1H,1H,2H,2H-Perfluorohexanesulfonic acid
1H,1H,2H,2H-Perfluorooctane sulfonic acid
1H,1H,2H,2H-Perfluorodecanesulfonic acid
Perfluoro-n-butanoic acid
Perfluoro-n-pentanoic acid
Perfluoro-n-hexanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-decanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-tetradecanoic acid
N-ethylperfluoro-1-octanesulfonamidoacetic acid
N-methylperfluoro-1-octanesulfonamidoacetic acid
Perfluorooctane sulfonamide
Method 8327 Native PFAS Standard | M-8327-10X
20 μg/mL in Methanol, 24 comps.| Purchase
Perfluorobutane-1-sulfonic acid
Perfluoropentanesulfonic acid
Perfluorohexane-1-sulfonic acid
Perfluoroheptanesulfonic acid
Perfluorooctane-1-sulfonic acid
Perfluorononanesulfonic acid
Perfluorodecane-1-sulfonic acid
1H,1H,2H,2H-Perfluorohexanesulfonic acid
1H,1H,2H,2H-Perfluorooctane sulfonic acid
1H,1H,2H,2H-Perfluorodecanesulfonic acid
Perfluoro-n-butanoic acid
Perfluoro-n-pentanoic acid
Perfluoro-n-hexanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-decanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-tetradecanoic acid
N-ethylperfluoro-1-octanesulfonamidoacetic acid
N-methylperfluoro-1-octanesulfonamidoacetic acid
Perfluorooctane sulfonamide
Absorbable Organic Fluorine (AOF) is another technique for the analysis of PFAS in liquid matrices where the Total concentration of Organic Fluorine compounds (TOF) is quantified instead of analyzing individual PFAS. USEPA Draft Method 1621 is designed for the determination of AOF in aqueous matrices using Combustion Ion Chromatography (CIC).
PFAS for Determination of Adsorbable Organic Fluorine (AOF) in Aqueous Matrices by Combustion Ion Chromatography (CIC)
EPA Draft Method 1621
Our M-1633 product series is offered to cover the 40 native PFAS required by USEPA Method 1633. USEPA Method 1633 is for the analysis of PFAS in aqueous, solid, biosolids and tissue samples using LC-MS/MS technique.
EPA Method 1633 Standards
M-1633-1-CN-10X
Varied Concentration in Acetonitrile, 11 comps.| Purchase
Perfluoro-n-butanoic acid
Perfluoro-n-pentanoic acid
Perfluoro-n-hexanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-decanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-tetradecanoic acid
M-1633-3A-CN-10X
20 µg/mL in Acetonitrile, 5 comps.| Purchase
Sulfluramid
Perfluorooctane sulfonamide
N-Methylperfluoro-1-octanesulfonamide
N-ethylperfluoro-1-octanesulfonamidoacetic acid
N-methylperfluoro-1-octanesulfonamidoacetic acid
M-1633-3B-CN-10X
100 µg/mL in Acetonitrile, 2 comps.| Purchase
N-Methylperfluorooctanesulfonamidoethanol
N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide
M-1633-4A-CN-R1-5X
Varied conc. in Acetonitrile, 8 comps.| Purchase
Perfluoro-3-methoxypropanoic acid
Perfluoro(4-methoxybutanoic) acid
Nonafluoro-3,6-dioxaheptanoic acid
Perfluoro(2-ethoxyethane)sulphonic acid
3-Perfluoropropyl propanoic acid
2H,2H,3H,3H-Perfluorooctanoic acid
2H,2H,3H,3H-Perfluorodecanoic acid
4,8-Dioxa-3H-perfluorononanoic acid
M-1633-4B-CN
2 µg/mL in Acetonitrile:Methanol (96:4), 2 comps.| Purchase
9-Chlorohexadecafluoro-3-oxanone-1-sulfonic acid
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid
ASTM Methods
This test method has been developed by USEPA region 5 through ASTM, D19 committee for the determination of PFAS in a soil matrix using LC-MS/MS. Our D-7968 CRM is prepared to contain all the 21 target native PFAS compounds in MeOH. Mixture is stabilized with NaOH to prevent acid esterification.
ASTM D7968 Native PFAS in Soil Standard | D-7968
2 µg/mL in Methanol, 21 comps.| Purchase
Perfluoro-n-tetradecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-decanoic acid
Perfluorooctane-1-sulfonic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-octanoic acid
Perfluorohexane-1-sulfonic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-hexanoic acid
Perfluorobutane-1-sulfonic acid
Perfluoro-n-pentanoic acid
Perfluoro-n-butanoic acid
2H,2H-Perfluorooctanoic acid
2H,2H-Perfluorodecanoic acid
2H,2H-Perfluorododecanoic acid
2H-Perfluoro-2-decenoic Acid
2H,2H,3H,3H-Perfluorodecanoic acid
2H-Perfluoro-2-octenoic acid
Perfluoro-4-ethylcyclohexane sulfonic acid
This test method is to qualify and quantify PFAS compounds in water matrix using LC-MS/MS. The D7979 CRM is formulated in include all the 21 target PFAS native compounds in MeOH stabilized with NaOH to enhance product stability.
ASTM D7979 PFAS in Wastewater Standard | D-7979
2 µg/mL in Methanol, 21 comps.| Purchase
Potassium perfluoro-1-butanesulfonate
Potassium perfluoro-1-hexanesulfonate
Perfluorooctane-1-sulfonic acid
Perfluoro-n-butanoic acid
Perfluoro-n-pentanoic acid
Perfluoro-n-hexanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-decanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-tetradecanoic acid
2H,2H,3H,3H-Perfluorodecanoic acid
2H-Perfluoro-2-decenoic Acid
2H,2H-Perfluorododecanoic acid
2H,2H-Perfluorodecanoic acid
2H-Perfluoro-2-octenoic acid
2H,2H-Perfluorooctanoic acid
Perfluoro-4-ethylcyclohexane sulfonic acid
ASTM test method D8421 is for the determination of PFAS in aqueous matrices by co-solvation and using LC-MS/MS technique. Our three Target Spike mix CRMs are offered to include the 44 native PFAS listed in the test method at a varied concentration. These CRMs are stabilized with NaOH to enhance product stability.
ASTM D8421 Native PFAS/PFOA Target Spike 1 Standard | D-8421-TS-1
2 µg/mL in MeOH:Water 95:5, 22 comps.| Purchase
Perfluoro-n-tetradecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-decanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-hexanoic acid
Perfluorodecane-1-sulfonic acid
Perfluorononanesulfonic Acid
Perfluorooctane-1-sulfonic acid
Perfluoroheptanesulfonic acid
Perfluorohexane-1-sulfonic acid
Perfluoropentanesulfonic acid
Perfluorobutane-1-sulfonic acid
Perfluorooctane sulfonamide
1H,1H,2H,2H-Perfluorodecanesulfonic acid
1H,1H,2H,2H-Perfluorooctane sulfonic acid
1H,1H,2H,2H-Perfluorohexanesulfonic acid
N-ethylperfluoro-1-octanesulfonamidoacetic acid
N-methylperfluoro-1-octanesulfonamidoacetic acid
ASTM D8421 Native PFAS/PFOA Target Spike 2 Standard | D-8421-TS-2
2 µg/mL in MeOH:Water 95:5, 19 comps.| Purchase
Perfluorododecanesulfonic acid
N-Methylperfluoro-1-octanesulfonamide
Sulfluramid
N-Methylperfluorooctanesulfonamidoethanol
N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide
Perfluoro(2-methyl-3-oxahexanoic) acid
4,8-Dioxa-3H-perfluorononanoic acid
9-Chlorohexadecafluoro-3-oxanone-1-sulfonic acid
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid
Nonafluoro-3,6-dioxaheptanoic acid
Perfluoro(2-ethoxyethane)sulphonic acid
Perfluoro-3-methoxypropanoic acid
Perfluoro(4-methoxybutanoic) acid
3-Perfluoropropyl propanoic acid
2H,2H,3H,3H-Perfluorooctanoic acid
2H,2H,3H,3H-Perfluorodecanoic acid
2H-Perfluoro-2-octenoic acid
2H-Perfluoro-2-decenoic Acid
Bis(trifluoromethane)sulfonimide lithium salt
ASTM D8421 Native PFAS/PFOA Target Spike 3 Standard | D-8421-TS-3
10 µg/mL in MeOH:Water 95:5, 3 comps.| Purchase
Perfluoro-n-pentanoic acid
Perfluoro-n-butanoic acid
2,2,3,3,3-Pentafluoropropionic acid
These CRMs are designed for the analysis of Fluorotelomer Alcohols (FTOHs) which are commonly used in the synthesis of PFAS compounds and in the manufacturing of different consumer products.
FTOHs in Test Chamber Air by TD-GC-MS/MS - ASTM Method D8591
ASTM D8591 Fluorotelomer Alcohols Stock Solution | D-8591
500 µg/mL in PT Methanol, 4 comps.| Purchase
1H,1H,2H,2H-Perfluorohexan-1-ol (2-Perfluorobutyl ethanol)
1H,1H,2H,2H-Perfluorooctan-1-ol
1H,1H,2H,2H-Perfluoro-1-decanol
1H,1H,2H,2H-Perfluorododecan-1-ol
Fluorotelomer Alcohols Mix 1 | FTOH-MIX-001
100 µg/mL in PT Methanol, 12 comps.| Purchase
1H,1H,2H,2H-Perfluorohexan-1-ol (2-Perfluorobutyl ethanol)
1H,1H,2H,2H-Perfluorododecan-1-ol
1H,1H,2H,2H-Perfluoro-1-decanol
1H,1H,2H,2H-Perfluorooctan-1-ol
1H,1H,2H,2H-Perfluoro-9-methyldecan-1-ol
1H,1H-Perfluorooctan-1-ol
1H,1H,2H,2H-Perfluorotetradecan-1-ol
1H,1H,10H,10H-Perfluoro-1,10-decanediol
1H,1H,2H,2H,3H,3H-Perfluorononan-1-ol
1H,1H-Perfluorononan-1-ol
1H,1H-Perfluorohexan-1-ol
1H,1H,5H-Perfluoropentan-1-ol
ISO Methods
This CRM supports the testing for PFAS in non-filtered water such as drinking water and wastewater using LC-MS/MS and according to the international standard. Our updated ISO21675 CRM includes the 29 native PFAS required by the test method and NaOH is added for enhanced stability. Perfluorooctadecanoic acid (PFODA) is available as a single component standard in both 2 µg/mL and 100 µg/mL concentrations in Methanol.
Native PFAS Reference Standard Set - ISO21675-PFAS-SET
2 x 1 mL - ISO21675-PFAS-R1, PFOA-029S-0.02X | Purchase Set
Although PFOA and PFOS production has significantly been reduced in recent years, both compounds continue to contaminate water sources due to their environmental persistence. This CRM is offered to test for PFOA and PFOS in drinking water, ground water and surface water using (HPLC-MS/MS.)
PFOS and PFOA Reference Standard | ISO25101
100 µg/mL in Methanol, 2 comps.| Purchase
Perfluorooctane-1-sulfonic acid
Perfluoro-n-octanoic acid
FDA Methods
FDA C-010.02 is one of the first test methods developed to address PFAS in food. The method procedure covers the testing of 16 PFAS found in infant formula, salmon, pancake syrup and other food matrices. PFAS-FDA is offered to include all 16 target PFAS in a multi component CRM.
FDA Method C-010.02 PFAS Reference Standard | PFAS-FDA
2 µg/mL in Methanol, 16 comps.| Purchase
Perfluoro-n-butanoic acid
Perfluoro-n-pentanoic acid
Perfluoro-n-hexanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-decanoic acid
Perfluorobutane-1-sulfonic acid
Perfluoropentanesulfonic acid
Perfluorohexane-1-sulfonic acid
Perfluoroheptanesulfonic acid
Perfluorooctane-1-sulfonic acid
Ammonium perfluoro(2-methyl-3-oxahexanoate) (GenX)
Potassium 9-chlorohexadecafluoro-3-oxanone-1-sulfonate
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid
Sodium dodecafluoro-3H-4,8-dioxanonanoate
These CRMs encompass all targeted compounds in AOAC Method 2023.003 for PFAS contaminants commonly found in produce, beverages, dairy products, eggs and other food dietary products. Mix 1 is prepared to include the main list of targeted analytes.
and Mix 2 includes the additional compounds to consider per AOAC 2023.003 for easy and accurate analysis.
PFAS in Food Reference Standard 1 | AOAC-PFAS-MIX-001
2 µg/mL in Acetonitrile, 30 comps.| Purchase
Perfluoro-n-butanoic acid
Perfluoro-n-pentanoic acid
Perfluoro-n-hexanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-octanoic acid
Perfluoro-n-nonanoic acid
Perfluoro-n-decanoic acid
Perfluoro-n-undecanoic acid
Perfluoro-n-dodecanoic acid
Perfluoro-n-tridecanoic acid
Perfluoro-n-tetradecanoic acid
Perfluorobutane-1-sulfonic acid
Perfluoropentanesulfonic acid
Perfluorohexane-1-sulfonic acid
Perfluoroheptanesulfonic acid
Perfluorooctane-1-sulfonic acid
Perfluorononanesulfonic acid
Perfluorodecane-1-sulfonic acid
Perfluoroundecanesulfonic acid
Perfluorododecanesulfonic acid
Perfluorotridecanesulfonic acid
Perfluorooctane sulfonamide
9-Chlorohexadecafluoro-3-oxanone-1-sulfonic acid
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid
Perfluoro(2-methyl-3-oxahexanoic) acid
4,8-Dioxa-3H-perfluorononanoic acid
1H,1H,2H,2H-Perfluorohexanesulfonic acid
1H,1H,2H,2H-Perfluorooctane sulfonic acid
1H,1H,2H,2H-Perfluorodecanesulfonic acid
1H,1H,2H,2H-Perfluorododecane sulfonic acid
PFAS in Food Reference Standard 2 | AOAC-PFAS-MIX-002
2 µg/mL in Acetonitrile, 10 comps.| Purchase
Mono[2-(perfluorooctyl)ethyl] phosphate
Mono[2-(perfluorohexyl)ethyl] phosphate
Bis[2-(perfluorohexyl)ethyl]phosphate
Sodium Bis(1H,1H,2H,2H-Perfluorodecyl)phosphate
Capstone A
Capstone B
1H,1H,2H,2H-Perfluorohexan-1-ol (2-Perfluorobutyl ethanol)
1H,1H,2H,2H-Perfluorooctan-1-ol
1H,1H,2H,2H-Perfluoro-1-decanol
1H,1H,2H,2H-Perfluorododecan-1-ol
State Method
This CRM includes all PFAS compounds that are listed in the Massachusetts DEP test guide for PFAS in drinking water. Also known as PFAS6, these compounds are specifically selected due to its high abundance in drinking water and the adverse health effects associated with its exposure.
Massachusetts PFAS Reference Standard | PFC-MA
2 µg/mL in Methanol, 6 comps.| Purchase
Perfluorooctane-1-sulfonic acid
Perfluoro-n-octanoic acid
Perfluorohexane-1-sulfonic acid (Linear and Branched)
Perfluoro-n-nonanoic acid
Perfluoro-n-heptanoic acid
Perfluoro-n-decanoic acid
Perfluoroalkylsulfonates
Perfluoroalkylcarboxylic acids and salts
Perfluorooctylsulfonamidoacetic acids
Perfluoroamides
Polyfluoroalkyl phosphate esters (PAPs)
Sulfonic acids
Telomer sulfonates
Fluorinated telomer alcohols (FTOHs)
Fluorotelomer methacrylates (FTMACs)
Fluorotelomer acrylates (FTACs)
Perfluoroalkyl acetates
Commercial / Technical grades
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